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Matthew P. Galloway, Ph.D.

Professor of Psychiatry and Behavioral Neurosciences
Wayne State University
School of Medicine

Office Address: Brain Research And Imaging Neurosciences (BRAINS)
                            Dept of Psychiatry and Behavioral Neurosciences
                            2126 Scott Hall 540 E. Canfield
                            Detroit, MI 48201

E mail: mgallow@med.wayne.edu

Phone: (313) 577-7598, (313)577-2914

Fax: (313) 993-4269

 

EDUCATION

St. Louis University
St. Louis, MO
Baccalaureate, Biology 1975
St. Louis University School of Medicine St. Louis, MO Graduate, Ph.D. in Biochemistry               Mentor: Dr. Carmine J. Coscia January 1981

Post-Doctoral Training

9/80 - 5/81 St. Louis University School of Medicine, Department of Pharmacology
Postdoctoral associate with Dr. Thomas C. Westfall
5/81 - 6/84 Yale University School of Medicine, Department of Pharmacology and Psychiatry
Postdoctoral fellow with Dr. Robert H. Roth

Professional Appointments

7/04 - Present Co-Director (Preclinical Imaging), Brain Res & Imaging Neurosciences
6/01 - 6/04 Director of Research Operations, Brain Imaging Research Division
8/96 - 6/98 Chief, Cellular and Molecular Neurobiology Research Division (rotating)
1997-2000 Director, Office of Research Administration, Dept. of Psychiatry
8/93 - Present Professor of Psychiatry and Behavioral Neurosciences (tenured)
1/90 - 1/92 Graduate Officer, Cellular & Clinical Neurobiology PhD Program
8/87 - 8/93 Associate Professor of Psychiatry FTA
8/84 - 8/93 Assistant Professor of Psychiatry FTA
7/84 - 12/92 Director, Neurochemical Pharmacology Research Unit (Lafayette Clinic)

PROFESSIONAL SOCIETIES:

Regular member, American College of Neuropsychopharmacology (1997)

Regular member, Society for Neuroscience

Michigan Chapter: Society for Neuroscience (President 1997-99)

SERVICE:

CONSULTANT and GRANT REVIEW EXPERIENCE

¨      NIDA: Regular member, NIDA-K, Training and Career Development   (Regular member 2/99-6/03; ad hoc 11/03-6/04; reappointed 7/04-6/07)

¨      NIDA: Training and Career Development Review Committee (ZDA-MXS-M-01): 4/98 -2/99 ad hoc [interim chair, Nov '98]

¨      NCRR ad hoc (Centers of Biomedical Research Excellence) March 2005

¨      NIEHS ad hoc (K awards) July 2004

¨      Life Sciences Greenhouse of Central Pennsylvania: Grant review 11/03

¨      NIMH B/START Ad hoc grant review, 1994, 1995, 1996

¨      NIDA Contract Proposal Review Committee (stimulant screening program, July 1990)

¨      NIDA Scientific Consultant for "CNS stimulants and new drug development" 1/91 - 9/93

¨      NSF Grant Review (Neuroscience Program, 1990)

¨      NINDS Special Review Committee, Program Project site visit (March 1989)

¨      NINDS Program Project Site Review, Ad Hoc member (May, 1989)

¨      Member, DATATOP Assay Committee (advise multicenter clinical study on biochemical aspects of assays of Parkinsonian CSF and plasma, 1987-1992)

UNIVERSITY COMMITTEE SERVICE:

(*Department of Psychiatry and Behavioral Neurosciences) 

*2005-07              Graduate Committee, Masters Training Program in Psychiatry

*1994-2000          Departmental Review Board, Chair

*1994-96              Joe Young Sr. Research Fund, Chair

*1993-95              Executive Committee, (basic science liaison to the Chairman)

*1997-00              Director, Office of Research Administration

*1996-02              Promotions and Tenure

*1995-00              Executive Research Directors Committee

*1994-99              Continuing Medical Education

*1996-7                Public Relations and Lobbying Task Force

*1994-                  Masters of Science in Psychiatry (Admissions, Program, Graduate)

*1990-1992           Graduate Officer, Cellular and Clinical Neurobiology PhD Training Program

*1985-92, 94-00    Graduate Committee, Cellular and Clinical Neurobiology PhD Program

*1994-5                Departmental clinical research program task forces: Schizophrenia and Mood Disorders, Substance Abuse, Program development

*1994-5                Renovations & Budget plan committee (MCHT and DRH)

*1990-1992           Executive Committee, Department of Psychiatry

*1990,1997           Internal Review Committee (Psychiatry); chair, basic research ('90)

*1984-90              Space and Equipment Advisory Committee, Lafayette Clinic

*1992                   Lafayette Clinic-Wayne State University Transition Committee 

2001-                   Research Development Committee, Medical School Faculty Senate

2001-03                Neuroscience Advisory Board (School of Medicine)

2001                     Strategic Planning for the School of Medicine

2001                     Perinatal Research Branch Contract, Exec Planning Committee

2001                     Committee to Enhance Postdoctoral Studies at WSU    

1999                     Strategic Planning Retreat: Basic Research & Education (School of Medicine)

1999                     Task Force for Non-Human Primate Studies (University)

1994-00                Animal Investigation Committee  (University)

1996                     Graduate Assistant awards (School of Medicine)

1995                     Rumble fellowship review; Graduate Professional fellowship review

1984-90                 Neuroscience Program Executive Committee, Wayne State University

1986-1990             Neuroscience Program Seminar Series Committee (Chairman), WSU

1987                     Scott Lecture and Neuroscience Colloquium Committee, WSU

External committee service: 

1997-99                 President, Michigan Chapter, Society for Neuroscience

1993-6                  Chair, Student Awards Committee, Michigan Chap: Society for Neuroscience

1996                     President-elect, Michigan Chapter: Society for Neuroscience

1997,98,99            Brain Awareness Lecture Series (high schools)

1997,98,99,00       Board of Directors, On My Own (independent living for challenged adults)

1997,98, 99,00      President, Board of Trustees, Fox Hills Community Association

 

TEACHING:        (At Wayne State University School of Medicine (1984-present) 

Graduate:           PYC 7010      Molecular Neuropsychopharmacology (Course Director 2002-)

                          IBS 7050      Medical Neurobiology (2005- )

                          MBG 7091     Scientific Communications (2003- )

                          PYC 701        Neurobiology I (annually, 1987-2000)

                          PYC 702        Neurobiology II (course director, annually, 1993-2000)

                          PYC 751        Neurochemistry of Monoamine Neurons (course director, 88-98)

                          PYC 789        Seminar (course director, 1988-89)

                          PYC 790        Directed Study

                          PYC 796        Laboratory rotation

                          ANA 719        Neuroscience Survey (1988-91)

                          PHC 701        Pharmacology: 5 lectures, psychopharmacology (1994-96)

                          PHC 755        Advanced Topics in Neurochemical Pharmacology

Ph. D Dissertations (M. Galloway, Primary Advisor): 

Raymond S. Salah, MD, PhD; 5/86 - 7/89,

      "Regulation of tyrosine hydroxylase activity in the rat striatum"

      Post doc: Univ of Michigan, Psychiatry residency & research fellow; private practice

Camille S. Suchowski (Norton), PhD 4/93- 9/97

Serotonin facilitation of dopamine release: neurochemical anatomy

Post-doc:  Univ of Michigan Sch Med (Dr. S. Watson);

Research Associate MHRC UM

Cheryl W. Aretha, PhD  8/93- 5/97

      The role of dopamine D3 receptors in the autoregulation of dopamine synthesis

      Post-doc: Univ of Mich Sch Med (Dr. M. Gnegy); WSU (Dr. D Kuhn);

      Lecturer, Baker College, Troy, MI (2003-) & Macomb Comm College (2004-)

Richard Nassar, PhD  10/93- 9/96

      Serotonergic modulation of tyrosine hydroxylase activity: An in vivo microdialysis study

      Post-doc: Yale Univ Sch Med (Dr. C. Bradberry);

Anthony West, PhD  1/94 - 8/97

      Characterization of nitric oxide-facilitated striatal dopamine and glutamate release in vivo: Role of ionotropic glutamate receptor -mediated mechanisms

      Post-doc: Univ of Pittsburgh (Dr. A. Grace); (1997-2002)

      Assistant Professor Neuroscience, Rosalind Franklin (Finch Univ)-Chicago Med Sch (2002)

Susanne Koch, PhD 1/94- 9/98

      Modulation of extracellular dopamine levels in rat brain by serotonin preferring psychostimulants and selective serotonin reuptake inhibitors

      Post-doc: Wayne State Univ Sch Med Brain Imaging (Dr. G. Moore);

      Research Fellow Lily Research Labs (2000-02, Dr Frank Bymaster)

      Lecturer, Fresno State College, Fresno, CA (2003-  )

Carrol D'Sa, PhD  1/97- 9/98

      Characterization of rat brain tryptophan hydroxylase:  In vitro and in vivo influence of iron

      Post-doc: Yale University Sch Med (Dr. R. Duman 1998-2001);

      Research Associate, Yale Univ (2002)

Navid Seraji-Bozorgzad (MD-PhD) 5/04 -

      Multivariate data analysis, affective disorders, and magnetic resonance spectroscopy

Master's Thesis in Basic Medical Sciences (MP Galloway, Primary Advisor)

Renee Maan 10/03-

      Neurochemical profile of cocaine determined with magnetic resonance spectroscopy

Kerry Murphy 05/04-

      Neurochemical profile of injectable and volatile anesthetics with HR-MAS 1H-MRS

Joel Frederick 09/04-

      Review of nicotine cessation strategies

Nicolle Aratari  5/98-2000

      Potential role of 5HT4 receptor activation in cocaine induced increases in dopamine

      Current: MD WSU-SOM 2004, Residency Henry Ford 7/04

Partha Mukhopadhyay  5/98-2000

      Respective role of dopamine and serotonin transporters in the action of cocaine

      Current: PhD graduate student (2003) Wisconsin

Mark Barsamian 2/94 - 1998

      Anxiogenic peptide regulation of dopamine release

 

Awards and honors for supervised students:

Raymond Salah:

       NIMH NRSA, 9/87, "Control of tyrosine hydroxylase in dopaminergic neurons"  F31 MH-09673;  Michigan Chapter: Society for Neuroscience, Duncan McCarthy Award, 1988

Camille Suchowski:

      Michigan Parkinson Foundation, 8/93, "Analysis of cerebrospinal fluid for 5-S-cysteinyl-DOPA and 6-hydroxydopamine"; Bernoucci Fellowship (Psychiatry) for Graduate Support 1995-96.

Anthony West:

      NRSA  F31 DA-05767 11/96 (2 yrs) "Regulation of striatal nitric oxide and dopamine release in vivo". WSU Rumble Fellow (94-95); Best poster, Michigan Chapter: Society for       Neuroscience meeting '95

Richard Nassar:

       WSU Rumble Fellow (95-96)

Susanne Koch:

        Best poster, Michigan Chapter: Society for Neuroscience meeting 1994; Duncan McCarthy Best Student Paper Award, 1997

Cheryl Wiley Aretha:

       Best poster, Michigan Chapter: Society for Neuroscience meeting,'96 

Carrol D'Sa:

       WSU Rumble Fellow

Todd Mitchell:

        NRSA F31 NS-043047 2002-04 “Mood Stabilizers and Neuroprotection”

Shonagh K. O'Leary-Moore:

        NRSA F31 AA-015224 2005-2008 “Neonatal Alcohol Exposure and 1H-NMR Imaging in Rats”

 

 

Graduate and Undergraduate Trainees

 

Name Institution Training Period Grad Training Deg
Kristen Haubenreich Univ of Mich May-Dec 2004 Northwestern Univ Proshetics-Orthotics Ctr (Certification) 2005
Kristen Prevost Albion College Jan-Jul 2005 MS: WSU SOM 2009
Steven Huffman Univ Colorado Summer 2003 MD: NY Med Coll 2008
David Briston Washington Univ Summer 2002 MS: WSU SOM 2005
Jamie Chioni Univ of Mich Summer 2001 DO: MSU SOM 2008
Mishal Mendirattta Kalamazoo Coll Summer 98 99 MD: WSU SOM Radiology, Henry Ford 2004
Robyn Sackeyfio Harvard Univ Summer 98    
Alzena Gallera Univ of Penn Summer 98    

 

Postdoctoral Trainees

Susan Benloucif, Ph.D. (UC Berkeley)  1/89 - 8/92

      Current:  Associate Professor, Molecular Pharmacology and Biological Chemistry, Northwestern University Medical School, Chicago, IL 

MaryAnn Chapman, Ph.D. (Washington State University)  12/96- 2/99

      Current: President, Visage Communications, Spokane, WA

External support 

Active:

·        R01-DA-016736 National Institute on Drug Abuse; High Field Magnetic Resonance Spectroscopy assessment of stimulant exposure in rats; MP Galloway, PI; GJ Moore, co-I; April 2004-2008; $1,324,000 (TC)

·        T32-DA-07310 National Institute on Drug Abuse: Training in Substance Abuse; DM Kuhn, PI; MP Galloway et al. co-I. June 2000-2005, $600,000 

·        R21 DA 019151 National Institute on Drug Abuse: A Preclinical Model of Adolescent Toluene Abuse in Rats SE Bowen, PI; MP Galloway, co-I. Sept 2004-Aug 2006 

Pending:

·        R01 ES 009977 National Institute of Environmental Health Sciences: Lead Toxicity-Midbrain Dopaminergic System, DK Pitts, PI, MP Galloway, consultant, July 2005-June 2009

 

Completed Projects 

Michael J Fox Foundation for Parkinson Research;

Ultra High Field MRS assessment of MPTP, Rotenone, and BSO effects in rodents;

MP Galloway, PI; GJ Moore co-I;

Jan 2003-11/30/04; $50,000 

 

National Institute on Drug Abuse

7/1/86 - 8/30/99                     R01-DA-04120

Cocaine and Amphetamine: Mesocortical Dopamine Neurons

MP Galloway, PI 

 

United Parkinson Foundation         

1/1/89

Pilot Studies on Gradient vs. One-Point Analysis of CSF HVA

MP Galloway, PI 

 

National Institute of Neurological Disorders and Stroke

4/1/90 - 3/31/93                     R01 NS-27892

Biological Markers in Parkinsons CSF

Peter LeWitt, PI

 

National Institute of Neurological Disorders and Stroke

7/1/87-6/30/92                       NS-24778

Deprenyl/tocopherol antioxidative therapy of Parkinsonism:

Subcontract for GC-MS analysis of CSF HVA

Ira Shoulson, PI

 

National Institute of Aging

4/1/88 - 3/30/96                     R01 AG-05233

Behavioral treatment of menopausal hot flashes

Robert Freedman, PI

 

National Heart, Lung, and Blood Institute

12/1/88-11/30/93                  R01 HL-30604

Behavioral treatment of Reynaud's phenomena

Robert Freedman, PI

 

National Institute on Alcohol Abuse and Alcoholism

12/1/92-11/30/97                  P50 AA-07606

Fetal alcohol exposure: From mechanism to prevention Project 3: "Effects on dopaminergic systems" (MP Galloway, PI)

Robert Sokol, PI program project

 

National Institute for Mental Health

8/1/86 ‑ 7/30/89                     R01 MH 41227

Serotonin Autoreceptors and Chronic Antidepressants

MP Galloway, PI

 

Pharmaceutical Manufacturers Association Foundation

1/1/86 - 12/31/87      (Researcher Starter grant)

Neuropharmacology of presynaptic serotonin neurons

MP Galloway, PI

 

Neurosciences Program-WSU

7/1/85- 6/30/86

Cocaine: Effects on mesocortical and mesolimbic dopamine neurons

MP Galloway, PI

 

United Parkinson Foundation

1/1/86 ‑ 12/31/86

Dopamine Autoreceptor Sensitivity After Chemical Lesions of Dopamine Neurons

MP Galloway, PI

 

National Institute on Drug Abuse

5/82-5/83                               F32-DA05209

Morphine in central noradrenergic systems

MP Galloway, PI (RH Roth, mentor)

 

National Institute for Mental Health

9/83-5/84                               F32-MH09102

Biochemical Pharmacology of Neuroleptics

MP Galloway, PI (RH Roth, mentor)


 

SELECTED PUBLICATIONS 

Roth, B.L., Galloway, M.P., and Coscia, C.J.  The effects of morphine on catecholamine metabolism during postnatal development.  Brain Res., 197:  561‑564, 1980. 

Galloway, M.P. Roth, B.L., and Coscia, C.J.  The effects of tetrahydroisoquinolinecarboxylic acids on tyrosine‑3‑monooxygenase, Arch. Biochem. Biophys. 209:  620‑627, 1981. 

Galloway, M.P., Burke, W.J. and Coscia, C.J.  Tetrahydroisoquinoline carboxylic acids and catecholamine metabolism in adrenal medulla explants.  Biochem. Pharmacol., 31:  3251‑3256, 1982. 

Galloway, M.P., and Westfall, T.C.  The release of endogenous norepinephrine from the coccygeal artery of spontaneously hypertensive and wistar‑kyoto rats.  Circ. Res., 51: 225‑232, 1982. 

Galloway, M.P. and Roth, R.H.  Clonidine prevents methylxanthine stimulation of norepinephrine metabolism in rat brain.J. Neurochem., 40:  246‑251, 1983. 

Galloway, M.P. and Roth, R.H.  The neuropharmacology of 3‑isobutylmethylxanthine:  Effects on central noradrenergic systems in vivoJ. Pharmacol. Exp. Therap., 227: 1‑8, 1983. 

Reinhard, J.F., Jr., Galloway, M.P. and Roth, R.H.  Noradrenergic modulation of serotonin synthesis and metabolism II:  Stimulation by 3‑isobutyl‑1‑methylxanthine.  J. Pharmacol. Exp. Ther.226:  764‑769, 1983. 

Charney, D.S., Redmond, D.E. Jr., Galloway, M.P., Kleber, H.D., Heninger, G.R., Murberg, M., and Roth, R.H.  Naltrexone precipitated opiate withdrawal in methadone addicted human subjects:  Evidence for noradrenergic hyperactivity.  Life Sci., 35: 1263‑1272, 1984.

Charney, D.S., Galloway, M.P., Heninger, G.R.  The effects of  caffeine on plasma MHPG, subjective anxiety, autonomic symptoms and blood pressure in healthy humans; Life Sci., 35: 135‑144, 1984. 

Grant, S.J., Galloway, M.P., Mayor, R., Fenerty, J., Finkelstein, M.F., Roth, R.H., and Redmond, D.E.  Precipitated diazepam withdrawal elevates noradrenergic metabolite in primate brain.  Eur. J. Pharmacol., 107: 127‑132, 1985. 

Galloway, M.P., Wolf, M.E. and Roth, R.H.  Regulation of dopamine synthesis in the medial prefrontal cortex is mediated by release modulating autoreceptors:  Studies in vivo.  J. Pharmacol. Exp. Ther.,236: 689-698, 1986. 

Wolf, M.E. Galloway, M.P. and Roth, R.H.  Regulation of dopamine synthesis in the medial prefrontal cortex:  Studies in brain slices.  J. Pharmacol. Exp. Ther., 236: 699-707, 1986. 

Salah, R.S., Kuhn, D.M., and Galloway, M.P., Dopamine autoreceptors modulate the phosphorylation of tyrosine hydroxylase in rat striatal slices.  J. Neurochem. 52: 1517-1522, 1989. 

Nelson, M.V., Berchou, R.C., LeWitt, P.A., Hussain, M., Kareti, D., Kesaree, N., Schlick, P., and Galloway, M.P.  Pharmacokinetic and pharmacodynamic modeling of levodopa plasma concentrations and clinical effects in parkinsons disease after Sinemet, Clinical Neuropharmacol., 12: 91-97, 1989. 

Martin, S.R. Yergani, V.K., Lohdi, R.A., and Galloway, M.P. Clinical ratings and plasma HVA during cocaine abstinence, Biol. Psychiatry, 26: 356-362, 1989 

The Parkinson Study Group, Effect of deprenyl on the progression of disability in early Parkinson's Disease, N. Engl. J. Med., 321: 1364-71, 1989. (MPG: Director, Cerebrospinal Fluid Assay Center; Member, Assay Standards Committee). 

Wachtel, S.R., Hu, X.T., Galloway, M.P., and White, F.J.  D1 Dopamine receptor stimulation enables the postsynaptic, but not autoreceptor, effects of D2 dopamine agonists in nigrostriatal and mesoaccumbens dopamine systems, Synapse, 4: 327-346, 1989. 

Nelson, M.V., Berchou, R.C., LeWitt, P.A., Kareti, D., and Galloway, M.P. Pharmacodynamic modeling of concentration-effect relationships after controlled-release carbidopa/levodopa (Sinemet CR4) in Parkinson's disease, Neurology, 40: 70-74, 1990. 

Galloway, M.P.  Regulation of dopamine and serotonin synthesis by acute administration of cocaine, Synapse, 6: 63-72, 1990. 

Hu, X.-T., Wachtel, S.R., Galloway, M.P., and White, F.J.  Lesions of the nigrostriatal dopamine projection increase the inhibitory effects of D1 and D2 dopamine agonists on caudate-putamen neurons and relieve D2 receptors from the necessity of D1 receptor stimulation.  J. Neurosci., 10: 2318-2329, 1990. 

Brooderson, R.B., White, F.J., and Galloway, M.P.  Inhibition of dopamine synthesis in striatal slices by the D1 agonist SKF 38393 is not mediated by D1 dopamine receptors.  Synapse, 6: 395-397, 1990. 

Clark, D., Salah, R.S., and Galloway, M.P. Differential agonist profile of the enantiomers of 3-PPP at striatal dopamine autoreceptors: Dependence on extracellular dopamine.  Synapse, 8: 169-176, 1991. 

Benloucif, S.B. and Galloway, M.P.  Facilitation of dopamine release in vivo by serotonin agonists: Studies with microdialysis.  Eur. J. Pharmacol., 200: 1-8, 1991.

Tyler, C.B., and Galloway, M.P. Acute administration of amphetamine: Differential regulation of dopamine synthesis in dopamine projection fields. J. Pharmacol. Exp. Ther., 261: 567-73, 1992. 

LeWitt, P.A., Galloway, M.P., Matson, W., Milbury, P., Srivastava, DK., Oakes, D., and The Parkinson Study Group.   Markers of dopamine metabolism in Parkinson's Disease. Neurology, 42:, 2111-2117, 1992. 

Benloucif, S.B., Keegan, M.J. and Galloway, M.P. Serotonin-facilitated dopamine release in vivo: Pharmacological characterization.  J. Pharmacol. Exp. Ther. 265:, 373-377, 1993. 

Galloway, M.P., Suchowski, C.S., Keegan, M.J., and Hjorth, S.  Local infusion of the selective 5HT-1b agonist CP-93,129 facilitates dopamine release in vivo.  Synapse 15:, 90-92, 1993. 1993. 

Freedman, R.R., Keegan, D., Rodriguez, J., and Galloway, M.P  Plasma catecholamine levels during temperature biofeedback training in normal subjects. Biofeedback Self Regul. 18 (2): 107-114, 1993. 

Hjorth, S, Suchowski, CS, and Galloway, MP  Evidence for 5HT autoreceptor-mediated, nerve impulse-independent, control of 5HT synthesis in the rat brain.  Synapse, 19: 170-176, 1995. 

Aretha, CW, Sinha, A. and Galloway, MP  Dopamine D3-preferring ligands act at synthesis modulating autoreceptors,  J. Pharmacol. Exp. Ther. 274:609-613,1995 

West, AR and Galloway, MP  Regulation of serotonin-facilitated dopamine release in vivo: The role of protein kinase A activating transduction mechanisms: Synapse 23:20-27, 1996 

Aretha, CW, and Galloway, MP Dopamine autoreceptor reserve in vitro: possible role of D3 receptors,  Eur. J. Pharmacol. 305:119-122, 1996 

West, AR and Galloway, MP Intrastriatal infusion of (+)-S-nitroso-N-acetylpenicillamine releases vesicular dopamine via an ionotropic glutamate receptor-mediated mechanism: An in vivo microdialysis study in chloral hydrate anesthetized rats.  J. Neurochem. 66:1971-1980, 1996 

Norton, CS and Galloway, MP  Repeated cocaine exposure attenuates the ability of 5-HT to release striatal dopamine in vivo.  Eur. J. Pharmacol. 318:323-326, 1996. 

Koch, S, Piercey, MF, Galloway, MP, Svensson, KA  Interactions between cocaine and (-)-DS 121: Studies with 2-deoxyglucose autoradiography and microdialysis in the rat brain. Eur. J. Pharmacol, 319: 173-180, 1997. 

Koch, S and Galloway, MP  MDMA induced dopamine release in vivo: Role of endogenous serotonin.  J. Neural Trans., 104: 135-146, 1997 

West, AR and Galloway, MP  Endogenous nitric oxide releases striatal dopamine and glutamate in vivo: Role of ionotropic glutamate receptor activation.  Neuropharmacol  36: 1571-81, 1997. 

West, AR and Galloway, MP   Inhibition of glutamate reuptake potentiates endogenous nitric oxide-facilitated dopamine efflux in the rat striatum: an in vivo microdialysis study  Neurosci. Lett., 229: 21-24, 1997 

West AR and Galloway MP  Nitric oxide and potassium chloride-facilitated striatal dopamine efflux in vivo: Role of calcium-dependent release mechanisms.   Neurochem Int  33: 493-501, 1999 

West, AR, Galloway, MP, and Grace AA Regulation of striatal dopamine neurotransmission by nitric oxide: Effector pathways and signaling mechanisms.  Synapse, 44: 227-245, 2002 

Moore GJ and Galloway MP Magnetic Resonance Spectroscopy: Neurochemistry and Treatment Effects in Affective Disorders.  Psychopharmacology Bulletin 36: (2) 1-23, 2002 

Chapman MA, Roll JM, Park S, Galloway MP Extracellular glutamate decrease in accumbens following cued food delivery. Neuroreport.  14 (7): 991-4, 2003 

Mitchell TR, Seraji-Bozorgzad N, Galloway MP, and Moore GJ.  Mood Stabilizers Lithium and Valproic Acid Afford Neuroprotection Against 3-Nitroproprionic Acid in Rats in preparation 2005 

Bustillo J, Barrow R, Paz R, Tang J, Seraji-Bozorgzad N, Moore GJ, Perrone-Bizzozero N, Bolognani F, Lauriello J, Galloway MP Long term treatment of rats with Haloperidol: Lack of an effect on N-acetylaspartate Neuropsychopharmacology in press 2005 

Mann R, Seraji-Bozorgzad N, Galloway MP. Metabolic Profile of Acute Cocaine in Rat Brain: Analysis with High Resolution Magic Angle Spinning Proton Magnetic Resonance Spectroscopy in preparation 2005 

REVIEW ARTICLES: 

Galloway, M.P., Neurochemical interactions of cocaine with dopaminergic systems,

Trends Pharmacol. Sci., 9: 451-454, 1988. 

Galloway, M.P. Augmentation of SSRI antidepressant efficacy with pindolol and the relevance of 5HT1A autoreceptors Anxiety, 2: 149-152, 1996. 

BOOK CHAPTERS 

Westfall, T.C., Galloway, M.P. Sax, R.D., Earnhardt, J.T., Leighton, H.J., Role of nerve impulse traffic and hypertension and prejunctional adrenoreceptor function, in Vascular Neuroeffector Mechanisms: 4th International Symposium, p. 117‑124, Ed., J. Bevan,  Raven Press, New York, 1983. 

Bennett, D.B., Galloway, M.P. Coscia, C.J.  Interaction of tetrahydroisoquinolines with activated tyrosine hydroxylase, in Beta‑Carbolines and Tetrahydroisoquinolines (Progress in Clinical and Biological Research, vol. 90),pp. 301‑310 Eds., F. Bloom, J.  Barchas, M.  Sandler, and E. Usdin, Alan R. Liss, Inc., New York, 1982. 

Billingsley, M.L., Galloway, M.P., and Roth, R.H.  Possible role of protein carboxylmethylation in the autoreceptor‑mediated regulation of dopamine neurons.  In:  Catecholamines, Part B:  Neuropharmacology and Central Nervous System‑Theoretical Aspects, Proceedings of the Fifth International Catecholamine Symposium, E.Usdin, A. Carlsson, A. Dahlstrom, and J. Engel, Eds., pp. 37‑41, Alan R. Liss, Inc., NY, 1984. 

Roth, R.H. Galloway, M.P., Tam, S‑Y, Ono, N., Wolf, M.E.  Dopamine autoreceptors:  Studies on their distribution and mode of action. In: Dopaminergic Systems and their regulation-IUPHAR Satellite Symposium,  Woodruff, G.N., Poat, J.A., Roberts, P.J., Eds., The MacMillan Press, Great Britain, 1986 

Levine, R.A. and Galloway, M.P., The regulation of monoamine synthesis and role of tetrahydrobiopterin. In: Unconjugated Pterins in Neurobiology: Basic and Clinical Aspects, W. Lovenberg and R.A. Levine, Eds., pp. 119-130, Taylor and Francis, Inc., London and Philadelphia, PA,  1987. 

Galloway, M. P. and Levine, R.A., Modulation of Dopamine Synthesis by Nerve Terminal Autoreceptors: A Role for Tetrahydrobiopterin?  In: Chemistry and Biology of Pteridines 1986,  B.A. Cooper and V.M. Whitehead, Eds., pp. 347-350, Walter de Gruyter & Co., Berlin, New York. 1986 

LeWitt, P.A. and Galloway, M.P., Implications of D-1 agonism for anti-parkinsonian therapeutics, In: Recent Developments in Parkinson's Disease Volume II,  S. Fahn, C.D. Marsden, D.B. Calne, M. Goldstein, Eds., pp. 75-89, Macmillan Healthcare Information, Florham Park, N.J. 1988 

LeWitt, P.A. and Galloway, M.P., Neurochemical markers of Parkinson's Disease, In: Therapeutics in Parkinson Disease, W. Koller and G. Paulson, Eds., pp.63-93,  Marcel Dekker Inc., New York, N.Y. 1990. 

Galloway, M.P.  Neuropharmacology of Cocaine: Effects on dopamine and serotonin systems. In Cocaine: Pharmacology, Physiology and Clinical Strategies, J.M. Lakoski, M.P. Galloway, and F.J.  White, Eds., pp. 163-189, CRC Press, Boca Raton Inc., FL, 1991. 

BOOKS EDITED 

Cocaine: Pharmacology, Physiology and Clinical Strategies, 443 pp. J.M. Lakoski, M.P. Galloway, and F.J.  White, Eds., CRC Press, Boca Raton Inc., FL, 1991. 

RECENT ABSTRACTS (978-2005 = 141) 

·    Galloway MP*, Fricke S, Mitchell TR, Seraji-Bozorgzad N, Moore GJ, MDMA (“Ecstasy”) Increases Striatal but not Prefrontal GABA in Rat Brain: Studies with High-Resolution Magic Angle Spinning Proton Magnetic Resonance Spectroscopy (HR-MAS 1H-MRS), 10th Ann Mtg of The International Society of Magnetic Resonance in Medicine, Abstract, Hawaii (2002).

·    Mitchell TR*, Galloway MP, Fricke ST, Seraji-Bozorgzad N, Zajac-Benitez C, Moore GJ  HR-MAS 1H Magnetic resonance spectroscopic characterization of striatal oxidative metabolic failure Abst 195.1. Soc for Neuroscience, 2002 Orlando

·    Galloway MP*, Seraji-Bozorgzad N, Fricke ST, Mitchell TR, Schoener EP, Moore GJ Differential effects of MDMA on GABA and glutamate in rat brain: Ex vivo analysis with high-resolution magic angle spinning magnetic resonance spectroscopy (HR-MAS-1H-MRS). Abst 135.11. Soc for Neuroscience, 2002, Orlando

·    Galloway MP*, Mitchell TR, Seraji-Bozorgzad N, Fricke ST, Posse S, and Moore GJ Neurochemical Utility of High Resolution Magic Angle Spinning 1H-Magnietic Resonance Spectroscopy (HR-MAS-MRS) at 11.7T: Effects of MDMA and Mitochondrial Failure in Rats.  American College for Neuropsychopharmacology, 40th Ann Mtg, San Juan 2002

·    Galloway MP*, Mitchell TR, Seraji-Bozorgzad N, Tancer ME, and Moore GJ  Neurochemical profile of acute MDMA in the rat: Assessment with high resolution magic angle spinning 1H-Magnetic resonance spectroscopy  (HR-MAS-MRS) at 11.7T. College on Problems in Drug Dependence, Annual Mtg, Bal Harbor, 2003

·    Galloway MP*, Mitchel TR, Seraji-Bozorgzad N, Moore GJ. Opposite Effects Of SKF38393 And MDMA On Striatal GABA And Accumbal Myo-Inositol: Studies With 1H Magnetic Resonance Spectroscopy At 11.7T. Program No. 113.1, New Orleans: Society for Neuroscience (Nov 2003).

·    Moore GJ, Mitchell TR, Alfano S, Seraji-Bozorgzad N, Galloway MP*. Analysis Of MR-Visible Neurochemicals In Rat Brain: Comparison Of Monoaminergic Soma And Projection Fields. Program No. 155.14, New Orleans: Society for Neuroscience (Nov 2003).

·    Galloway MP*, Huffman S, Alfano S, Seraji-Bozorgzad N, Mitchell TR, Moore, GJ  Assessment of Antidepressant Effects on Rat Brain GABA with High Resolution 1H Magnetic Resonance Spectroscopy at 11.7 T , American College of Neuropsychopharmacology Meeting, San Juan PR,  (Dec 2003).

·    SK O’Leary-Moore*, TR Mitchell, AP McMechan, SN Mathison, GJ Moore, MP Galloway, & JH Hannigan. Fetal Alcohol Alters Cerebellar Neurochemistry: High-Resolution Magic Angle Spinning 1H Magnetic Resonance Spectroscopy (HR-MAS 1H MRS) at 11.7T  International Soc Developmental Psychobiology Meeting, Aix-en-Provence, France (June 2004)

·    N. Seraji-Bozorgzad*; S. Huffman, J. Tang, G.J. Moore, M.P. Galloway   Effects of SSRI Antidepressants On HR-MAS 1H-MRS Metabolomic Profile In Rat Brain At 11.7T.  Society for Neuroscience (Oct 2004) San Diego, CA 

·    T.W. Uhde*, M.P. Galloway, J. Fang, T.R. Mitchell, E.O. Bixler, G.J. Moore.  Sleep Deprivation Increases Excitatory Amino Acids in the Prefrontal Cortex: Studies with Magnetic Resonance Spectroscopy at 11.7T. Society for Neuroscience (Oct 2004) San Diego, CA

·    S. K. O’Leary-Moore*, N. Seraji-Bozorgzad, T.R. Mitchell, G.J. Moore, M.P. Galloway, & J. H. Hannigan.  Developmental Changes in Regional Neurochemistry Using High-Resolution Magic Angle Spinning 1H-Magnetic Resonance Spectroscopy (HR-MAS 1H MRS) at 11.7T. Society for Neuroscience (Oct 2004) San Diego, CA

·    M.P. Galloway, S. Huffman, K.M. Haubenreich*, M.J. Brucal*, N. Seraji-Bozorgzad, T.R. Mitchell, G.J. Moore.  Neurochemical Profile Of Dopamine Cell Loss After 6OHDA or MPTP: Analysis With 1H Magnetic Resonance Spectroscopy At 11.7T.  Society for Neuroscience (Oct 2004) San Diego, CA

·    R.R. Maan*; J. Tang, N. Seraji-Bozorgzad, T.R. Mitchell, G.J. Moore, M.P. Galloway Neurochemical Profile Of Cocaine In The Rat: Metabolomic Analysis With 1H Magnetic Resonance Spectroscopy At 11.7T.  Society for Neuroscience (Oct 2004) San Diego, CA 

·    T.R. Mitchell*, J. Tang, N. Seraji-Bozorgzad, M.P. Galloway, G.J. Moore Neuroprotection Afforded By Lithium Against 3-Nitroproprionic Acid: Neurochemical And Anatomical Studies With Magnetic Resonance At 11.7 Tesla. Society for Neuroscience (Oct 2004) San Diego, CA

·    G.M. McKelvey*, H.M. Marsh, A. Pustavoitau, T.R. Mitchell, N. Seraji-Bozorgzad, G.J. Moore, M.P. Galloway.  Common Effects Of Halothane And Isofluorane On The Neurochemical Profile Rat Brain: Studies With High-Resolution Magic Angle Spinning 1H-Magnetic Resonance Spectroscopy (HR-MAS-1H-MRS) At 11.7T. Society for Neuroscience (Oct 2004) San Diego, CA

·    T. Uhde, M. Galloway*, J Fang, T. Mitchell, E. Bixler, B. Cortese, R. Singareddy, A Vgontzas, M McEchron, G. Moore.  Sleep Deprivation and Excitatory Amino Acids, American College of Neuropsychopharmacology Annual Mtg, San Juan PR,  (Dec 2004).

·    N. Seraji-Bozorgzad, KM Haubenreich, J Tang, GJ Moore, and MP Galloway*.  Correlations between the neurochemical profile determined with 1H-magnetic resonance spectroscopy at 11.7 T and dopamine and serotonin activity in rat brain: Effects of challenge with serotonergic agents, American College of Neuropsychopharmacology Annual Mtg, San Juan PR,  (Dec 2004).

·    Mitchell TR*, Seraji-Bozorgzad N, Galloway MP, Moore GJ   Mood Stabilizers Protect Against a Huntington's Disease Animal Model: A Multi-Modal MR Study at 11.7 T.  13th Ann Mtg of International Society for Magnetic Resonance in Medicine, Miami FL (May 2005)

·    KL Murphy*, G. McKelvey, A. Pustavoitau, N. Seraji-Bozorgzad, MP Galloway, HM Marsh The Effects of Volatile and Injectable Anesthetics on the Neurochemical Profile in Rat Brain: Studies with High Resolution Magic Angle Spinning 1H Magnetic Resonance Spectroscopy (HR-MAS-1H-MRS) at 11.7 T  52nd Ann Mtg Assoc University Anesthesiologists Baltimore MD, (May 2005).

·    S K O’Leary-Moore*, N. Seraji-Bozorgzad, M P Galloway, and JH Hannigan Neurochemical profile of fetal alcohol exposure: Analysis with 1H-magnetic resonance spectroscopy at 11.7 Tesla.  Research Society on Alcoholism 28th Annual Mtg, Santa Barbara CA (June 2005)

·    GM McKelvey*; KL Murphy, A. Pustavoitau, N. Seraji-Bozorgzad, KE Prevost, SK O'Leary Moore, GL Moore, HM Marsh, MP Galloway.  NMDA receptor antagonism with ketamine selectively increases GABA measured with proton magnetic resonance spectroscopy. Society for Neuroscience (Nov 2005) Washington, DC 

·    KL Murphy*; GM McKelvey, SK O'Leary-Moore, N. Seraji-Bozorgzad, DC Freeman, A. Pustavoitau, KM. Haubenreich, GJ Moore, HM Marsh, MP Galloway. Potentiation of GABA-A receptor function with propofol selectively decreases glutamate measured with proton magnetic resonance spectroscopy. Society for Neuroscience (Nov 2005) Washington, DC 

·    MP Galloway*; SK O'Leary-Moore, N Seraji-Bozorgzad, HM Moore, GM Miller, SG Rayport. Probing the Nature of MR-Visible Neurochemicals using Trangenic Mice Lacking Glutaminase and High-Resolution Magic Angle Spinning 1H Magnetic Resonance Spectroscopy.  Society for Neuroscience (Nov 2005) Washington, DC

·    N. Seraji-Bozorgzad*; S. O'Leary-Moore; MP Galloway.  Coupling of MR visible GABA, glutamate and glutamine to metabolic and neuronal pathways. Society for Neuroscience (Nov 2005) Washington, DC

·    S.K. O'Leary-Moore*, AP McMechan, N. Seraji-Bozorgzad, KE Prevost, JH Hannigan, MP Galloway. Acute Ethanol Exposure Alters the Metabolomic Profile in Rat Brain as Measured by Magic Angle Spinning 1H Magnetic Resonance Spectroscopy (HRMAS 1H MRS) Society for Neuroscience (Nov 2005) Washington, DC

·    SK O’Leary-Moore*, AP McMechan, DR Williams, MP Galloway,  JH Hannigan, SE Bowen Region-Dependent Alterations in Brain Glutamate, GABA and Glutamine Levels after Acute Toluene Exposure in Juvenile Rats Measured by High-Resolution 1H Magnetic Resonance Spectroscopy at 11.7 Tesla  International Soc Developmental Psychobiology Meeting (Nov 2005) Wash, DC 

·    Galloway, MP*; Seraji-Bozorgzad, N; Murphy, KL; O'Leary Moore, SK; Haubenreich, KM; McKelvey, GM; Pustavoitau, A; Hannigan, JH; Marsh, HM. Increased GABAergic Activity Modulates MR-Visible Glutamate and Glutamine: Studies with High Resolution Magic Angle Spinning Proton Magnetic Resonance Spectroscopy (HR-MAS 1H-MRS) American College of Neuropsychopharmacology Annual Mtg, Waikolao, HI,  (Dec 2005). 

·    Bustillo, JR*;  Perrone-Bizzozero, N, Paz, R, Griffith, G, Galloway, M  Hypometabolic medial-frontal effects of chronic intermittent PCP exposure in rats assessed with high resolution magic angle spin 11.7T proton magnetic resonance spectroscopy  American College of Neuropsychopharmacology Annual Mtg, Waikolao, HI,  (Dec 2005). 

 

 

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